SAFER Guides

The 2025 SAFER guides have been updated and streamlined to focus on the highest risk, most commonly occurring issues that can be addressed through technology or practice changes to build system resilience.

The 2025 SAFER Guides consist of eight guides organized into three broad groups. These guides enable healthcare organizations to address EHR safety in a variety of areas. Most organizations will want to start with the Foundational Guides and proceed from there to address their areas of greatest interest or concern. The guides identify recommended practices to optimize the safety and safe use of EHRs. The content of the guides can be explored here, at the links below, or interactive PDF versions of the guides can be downloaded and completed locally for self-assessment of an organization’s degree of conformance to the Recommended Practices.

2016 SAFER Guides

The previous versions of the SAFER Guides, published in 2016, continue to be applicable for the SAFER Guides measures included in the Medicare Promoting Interoperability Program for eligible hospitals and CAHs and the Promoting Interoperability performance category of the Merit Based Incentive Payment System (MIPS). You can learn more about the SAFER Guides measures in these programs and relevant requirements from the CMS SAFER Guides Infographic [PDF - 301 KB]

Foundational Guides

Infrastructure Guides

Clinical Process Guides